Dendritic cells induce T cell proliferation to synthetic antigens under Ir gene control
نویسندگان
چکیده
Dendritic cells prepared by a modification of the method of Steinman and Cohn are I-A+ and FcR-. They are extremely potent at activating not only allogeneic T cell proliferation but also antigen-specific syngeneic T cell proliferation. Dendritic cells from nonresponder strains are unable to present antigens to responder X nonresponder T cells, suggesting that they may be a site of Ir gene product expression.
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 152 شماره
صفحات -
تاریخ انتشار 1980